Carrying out clinical studies means collecting information about patients and investigators, and a CRF (case report form) in printed, optical or electronic form has been designed to collect and transmit to the sponsor all the information required by the protocol for every participant in the clinical study (ICH IV, 1996).

Doing studies with electronic CRFs makes it easier to do and control the study, as well as reducing the number of queries present in the study. That is why, at present, there is a great tendency to carry out studies by way of electronic CRFs.

3D Health offers its electronic CRF creation service that can implement recognised electronic signature.  This factor will becomes easier because of the fact that medical professionals will shortly, or already, have recognised digital certificates so as to issue electronic prescriptions.